Actores:
Johnny Galecki (Leonard Hofstadter)
Jim Parsons (Sheldon Cooper)
Kaley Cuoco (Penny)
Simon Helberg (Howard Wolowitz)
Kunal Nayyar (Rajesh Koothrappali)
Mayim Bialik (Amy Farrah Fowler)
Melissa Rauch (Bernadette Rostenkowski)

Productores Ejecutivos:
Chuck Lorre
Bill Prady
Lee Aronsohn
Steven Molaro

Creadores:
Chuck Lorre
Bill Prady